产品货号：
Z19820
中文名称：
KISS1抗体
英文名称：
Anti-KISS1 Antibody (N-Term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-KISS1 Antibody (N-Term) |
| 指标别名 | KiSS 1;KiSS 1 metastasis suppressor;KISS1;Kisspeptin 1;Metastasis suppressor KiSS 1;metastin |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | KISS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This KISS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-52 amino acids from human KISS1. |
| 计算分子量 | 15kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Metastasis suppressor protein in malignant melanomas and in some breast cancers.May regulate events downstream of cell- matrix adhesion,perhaps involving cytoskeletal reorganization.Generates a C-terminally amidated peptide,metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54.Activation of the receptor inhibits cell proliferation and cell migration,key characteristics of tumor metastasis.Kp-10 is a decapeptide derived from the primary translation product,isolated in conditioned medium of first trimester trophoblast.Kp-10,but not other kisspeptins,increased intracellular Ca (2+) levels in isolated first trimester trophoblasts.Kp-10 is a paracrine/endocrine regulator in fine- tuning trophoblast invasion generated by the trophoblast itself.The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty.The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. |
| Uniprot ID | Q15726 |
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